Best route from Victoria, Tx to Hope, Ar without going through Houston

You've been given a bunch of good routes, here's another copied from Google Map:

Take US-77 N, US-79 N, State Hwy 155 N, US-59 N and I-30 E to US-278 E/N Hervey St in Hope. Take exit 30 from I-30 E
7 hr 44 min (446 mi)​

This should help your time also...of course, this is all based on no interfering traffic.
It's the same as drvtech77, but with numbers.

 

We used to run from the Anderson Ranch or King Ranch up through Victoria on 77 for a stop in LaGrange then hit 79 in Rockdale to 69 in Jacksonville on up to Tyler for a stop. Then go down Interstate 20 east to 59N to go on up to the Texarkana corner. That was a long time ago in the double nickel days. Lol!

 

Just bite the bullet and hit Houston after 9pm.

 

Victoria, TX to Hope, AR - Google Maps

 

That's exactly what I'd do. Good call, @Dennixx .

Be paying attention to the signs in Henderson, "the star" is a tricky intersection. Wouldn't surprise me if it used to be a traffic circle once upon a time.

 

Don't know what route was taken but this is a under 10 hr route even primarily 2 lane

 

Sorry I missed this.

Looks like a couple good routes got posted. Personally I'd probably bite the bullet and run right up 59 through Houston and keep on going N till I hit Texarkana. Then I'd jump off at exit 18, go under 30 and go right on 67 and take that right into Hope.