I’ve got a nail in my drive tire and a hot load.

dude.....you could go to just about any truckstop and have them plug it in 30 minutes or less.
On the other hand, you could stop every 200-300 miles and put air in it

 

good chance it could start leaking down.

or not.

I'd pull it and see if it went through. use widow cleaner to check for bubbles.

 

Spray water or glass cleaner if it's not leaking run it. Just check when ever you stop. Have it fixed after you deliver.

 

50/50

Did you soap check to see if it was leaking air, or just listen?

Could be a short nail that hasn't fully penetrated the tread, or a long spike that is just gonna cause a bigger hole through the constant pounding.

If the tire DOES have a slow leak, your chances of a blowout dramatically increase, and a blowout will DEFINITELY make you late.

I know what I'd do, but you do you.

Good luck.

 

Do you have a air line/nozzle to hook to your gladhand?
If so stop at the nearest parts shop or decent truck stop and grab a plug kit so you can do it yourself.

Truck Tire Repair, Heavy Equipment Tire Repair Kits, Tire Repair Plug Kit | Safety Seal

 

so find a truck stop on your route that can fix the tire during either your 10hr or your 30min break. It's called trip planning and calling ahead. Then you're gonna be stopped at that time anyways. you're risking it blowing and being in a ditch and not delivering your load at all. Why risk it?

 

Air hose and plug kit.

2 handy items to have.